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Effects of Flurbiprofen Spray and Ice Cream for Pain and Voice Outcomes After Thyroidectomy
Sponsor: Izmir Katip Celebi University
Summary
Researchers will compare oral flurbiprofen (%0.25) spray and ice cream to a placebo (a look-alike substance that contains no drug) to see if oral flurbiprofen (%0.25) spray and ice cream works to effect post-thyroidectomy throat pain and voice quality. Participants will: * Receive 1 puff of oral flurbiprofen (0.25%) spray or 105 ml of ice cream or 1 puff of oral spray prepared with drinking water (placebo) at 5 hours postoperatively according to randomization result * Undergo voice analysis using Praat voice analysis (University of Amsterdam) at 6 hours postoperatively * Undergo a visual analog scale for analgesia status at 6 hours postoperatively
Official title: Comparison of the Effects of Postoperative Oral Flurbiprofen (0.25%) Spray and Ice Cream on Analgesia and Voice Quality in Patients Undergoing Thyroidectomy
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-04
Completion Date
2026-09
Last Updated
2026-04-15
Healthy Volunteers
No
Conditions
Interventions
Flurbiprofen
This group will receive one puff of oral flurbiprofen (0.25%) spray (for pain palliation) at 5 hours post-operatively.
Food Effect cohort
This group will receive 105 ml of frozen ice cream at 5 hours post-operatively
Placebo Control
This group will receive one puff of spray prepared with drinking water at 5 hours post-operatively as a placebo.
Locations (1)
Izmir Katip Celebi University
Izmir, Turkey (Türkiye)