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Echocardiographic Assessment of the Effect of Impella on Biventricular Function
Sponsor: University of Rochester
Summary
The objective of this prospective observational study is to evaluate the effects of Impella 5.5 on biventricular function in adult patients with end-stage heart failure requiring temporary mechanical circulatory support. The study will assess changes in left and right ventricular global longitudinal strain and myocardial work, as well as additional echocardiographic and hemodynamic parameters. Measurements will be obtained at baseline prior to Impella implantation, immediately after device initiation, and during postoperative follow-up between 7 and 14 days. This study involves collection of echocardiographic imaging and clinical data, including additional imaging performed for research purposes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
24
Start Date
2026-04-15
Completion Date
2027-04-15
Last Updated
2026-04-16
Healthy Volunteers
No
Conditions
Interventions
Echocardiographic Assessment
Echocardiographic imaging will be performed at baseline prior to Impella implantation, immediately after device initiation, and during postoperative follow-up between Day 7 and Day 14 to assess biventricular function.