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Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
Sponsor: Erzincan Binali Yildirim Universitesi
Summary
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
Official title: Evaluation of the Safety of Low-Flow Anesthesia Initiated Without Wash-in in Terms of Oxygenation and Depth of Anesthesia Using Arterial Blood Gas Analysis and EEG-Based PSI Monitoring
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-03-01
Completion Date
2026-08-01
Last Updated
2026-04-16
Healthy Volunteers
Yes
Conditions
Interventions
Initiation of low-flow anesthesia without wash-in following intubation
After endotracheal intubation, fresh gas flow is set to 0.75 L/min with 60% O₂. The sevoflurane vaporizer is initially set to 8%, and the sevoflurane concentration is subsequently titrated according to the target MAC value. Anesthesia depth and oxygenation are monitored using PSI monitoring and serial arterial blood gas measurements.
Locations (1)
Binali Yildirim Univercity
Erzincan, Erzincan, Turkey (Türkiye)