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RECRUITING
NCT07535619

The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.

Sponsor: Aalborg University Hospital

View on ClinicalTrials.gov

Summary

The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the study aims to investigate if the microbiota is different according to the severity of DUI and if the microbiota is changed throughout treatment of DUI. A follow-up study will as well be performed on healthy children to investigate how the microbiota evolves with increasing age and pubertal stage. Children with OAB and DUI will be recruited from involved pediatric departments, and specimen in the form of urine, perineal/preputial swabs, and feces will be collected according to the protocol.

Official title: The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children and Adolescents - the PpUF-study.

Key Details

Gender

All

Age Range

5 Years - 17 Years

Study Type

OBSERVATIONAL

Enrollment

110

Start Date

2022-12-14

Completion Date

2028-06

Last Updated

2026-04-17

Healthy Volunteers

Yes

Locations (4)

Department of Pediatrics, Aalborg University Hospital

Aalborg, Denmark

Department of Pediatrics, Aarhus University Hospital

Aarhus, Denmark

Department of Pediatrics, Regional Hospital West Jutland

Herning, Denmark

Department of Pediatrics, North Denmark Regional Hospital

Hjørring, Denmark