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The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
Sponsor: Aalborg University Hospital
Summary
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the study aims to investigate if the microbiota is different according to the severity of DUI and if the microbiota is changed throughout treatment of DUI. A follow-up study will as well be performed on healthy children to investigate how the microbiota evolves with increasing age and pubertal stage. Children with OAB and DUI will be recruited from involved pediatric departments, and specimen in the form of urine, perineal/preputial swabs, and feces will be collected according to the protocol.
Official title: The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children and Adolescents - the PpUF-study.
Key Details
Gender
All
Age Range
5 Years - 17 Years
Study Type
OBSERVATIONAL
Enrollment
110
Start Date
2022-12-14
Completion Date
2028-06
Last Updated
2026-04-17
Healthy Volunteers
Yes
Conditions
Locations (4)
Department of Pediatrics, Aalborg University Hospital
Aalborg, Denmark
Department of Pediatrics, Aarhus University Hospital
Aarhus, Denmark
Department of Pediatrics, Regional Hospital West Jutland
Herning, Denmark
Department of Pediatrics, North Denmark Regional Hospital
Hjørring, Denmark