Clinical Research Directory

Inclusion Criteria: 1. Patients with a confirmed diagnosis of traumatic brain injury (clinical and/or radiological), including both surgical and conservative management 2. Admission within 24 hours of injury 3. Eligible for antiepileptic prophylaxis according to clinical guidelines 4. Written informed consent obtained. Exclusion Criteria: 1. Pre-existing epilepsy or seizure disorder. 2. Seizure episode before or during admission unrelated to acute TBI. 3. Prior use of antiepileptic drugs before admission. 4. Severe renal impairment (creatinine clearance \<30 mL/min). 5. Hepatic failure. 6. Pregnancy or lactation. 7. Known hypersensitivity to antiepileptic drugs