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Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis
Sponsor: University of Chile
Summary
The goal of this observational study is to examine JAK1/2 pathway activation in gingival tissues from adults with healthy gingiva and those with inflamed gingiva (periodontitis). The main question it aims to answer is: Is the JAK1/2 pathway overactivated in periodontitis compared to health? Participants with healthy gingiva and periodontitis will donate gingival tissue to study the JAK1/2 pathway. All participants wil receive diagnosis and treatment of the gingival condition.
Official title: Unraveling the Role of JAK1 and JAK2 Pathway in Periodontitis: Drivers of Immunopathology and Possible Therapeutic Targets
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2023-06-01
Completion Date
2027-03-31
Last Updated
2026-04-17
Healthy Volunteers
Yes
Conditions
Locations (1)
Faculty of Dentistry, University of Chile
Santiago, Metropolitan Region, Chile