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Leukemia Stem Cell-based Assay to Predict Relapse and Survival in Patients With Acute Myeloid Leukemia
Sponsor: Peking University People's Hospital
Summary
The goal of this observational study is to learn about the predict value of leukemia stem cell for acute myeloid leukemia patients with MLL-rearrangement. The main question it aims to answer is: • Could be leukemia stem cell used for relapse prediction in acute myeloid leukemia patients with MLL-rearrangement? Leukemia stem cell will be detected at the same time for participants who detected minimal residual disease using bone marrow as part of their regular medical care to answer the question.
Key Details
Gender
All
Age Range
6 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
210
Start Date
2025-06-01
Completion Date
2026-04-07
Last Updated
2026-04-17
Healthy Volunteers
No
Interventions
Detection of leukemia stem cell using multiparameter flow cytometry
For AML patients with MLL rearrangement enrolled, leukemia stem cell will be detcted at diagnosis and during follow-up. A traditional Minimal residual disease was deteced as normal medical care, simultaneously, leukemia stem cell will be detcted using the sample bone marrow sample.
Locations (1)
Peking University People's Hospital
Beijing, China