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MCE Molecular Imaging for Myocarditis
Sponsor: University of Virginia
Summary
Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it. The purpose of this study is to determine whether myocarditis such as that which occurs with viral illness, autoimmune conditions, or certain therapies (i.e. immune checkpoint inhibitors) can be diagnosed using a new form of ultrasound imaging of the heart (echocardiography) that uses a contrast agent that is targeted to inflammation (Sonazoid).
Official title: MCE Molecular Imaging in Myocarditis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-09-15
Completion Date
2030-07-01
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Myocardial contrast echocardiography molecular imaging for inflammation
Myocardial contrast echocardiography (ultrasound of the heart) using an ultrasound contrast agent (Sonazoid, GE Healthcare) that contains phosphatidylserine, thereby targeting it to leukocytes and activated endothelium.
Locations (1)
University of Virginia
Charlottesville, Virginia, United States