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NOT YET RECRUITING
NCT07538544
EARLY_PHASE1

MCE Molecular Imaging for Myocarditis

Sponsor: University of Virginia

View on ClinicalTrials.gov

Summary

Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it. The purpose of this study is to determine whether myocarditis such as that which occurs with viral illness, autoimmune conditions, or certain therapies (i.e. immune checkpoint inhibitors) can be diagnosed using a new form of ultrasound imaging of the heart (echocardiography) that uses a contrast agent that is targeted to inflammation (Sonazoid).

Official title: MCE Molecular Imaging in Myocarditis

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-09-15

Completion Date

2030-07-01

Last Updated

2026-08-20

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Myocardial contrast echocardiography molecular imaging for inflammation

Myocardial contrast echocardiography (ultrasound of the heart) using an ultrasound contrast agent (Sonazoid, GE Healthcare) that contains phosphatidylserine, thereby targeting it to leukocytes and activated endothelium.

Locations (1)

University of Virginia

Charlottesville, Virginia, United States