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RECRUITING
NCT07538648
PHASE1

A Phase II Clinical Study Evaluating the Effectiveness of Injectable NC527-X in Intraoperative Imaging for Patients With Solid Tumors

Sponsor: Zhejiang Cancer Hospital

View on ClinicalTrials.gov

Summary

Evaluate the initial dose-effect and time-effect relationship of the injection product NC527-X

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2025-12-24

Completion Date

2027-06-30

Last Updated

2026-04-20

Healthy Volunteers

No

Conditions

Interventions

DRUG

Experimental:Preoperative injection of NC527-X

This study will set up four single-arm dose groups (A, B, C, D), and it will be conducted in patients with solid tumors who have been diagnosed and are scheduled for surgical resection (evaluated by the researchers to have no surgical contraindications). The study will initially assign patients to groups A, B, C, and D respectively, with each group planning to include at least 3 cases, and a total of no more than 100 cases will be enrolled. The dosages will be 0.005 mg/kg, 0.01 mg/kg, 0.02 mg/kg, and 0.04 mg/kg, and the imaging time window after administration will be 24 to 72 hours.

Locations (1)

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China