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AI-Assisted Staging and Treatment Decision-Making for Hepatocellular Carcinoma
Sponsor: Beijing Tsinghua Chang Gung Hospital
Summary
The precise treatment of primary hepatocellular carcinoma (HCC) highly depends on accurate disease staging (CNLC, TNM, BCLC) and scientific treatment decision-making, which necessitate the integration of both imaging and clinical baseline data. This study prospectively recruits HCC patients and clinical physicians across different hospital tiers to evaluate the clinical value of a self-developed artificial intelligence (AI) model in assisting multi-dimensional comprehensive assessment and treatment decision-making. Utilizing a Multi-Rater Multi-Case (MRMC) crossover balanced design, the study compares the accuracy of clinical evaluations performed by physicians under "unassisted (without AI)" versus "AI-assisted" conditions. A key focus is to explore whether AI can significantly enhance the comprehensive assessment capabilities of physicians in primary/secondary care hospitals, thereby prospectively reducing diagnostic and therapeutic heterogeneity across different institutional levels.
Official title: A Prospective, Randomized, Controlled, Crossover Study of Artificial Intelligence-Assisted Multi-Dimensional Staging and Treatment Decision-Making for Hepatocellular Carcinoma
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
108
Start Date
2026-04-13
Completion Date
2026-05-20
Last Updated
2026-04-20
Healthy Volunteers
No
Conditions
Interventions
Unassisted Independent Evaluation
Physicians independently evaluate the HCC cases and provide staging and treatment decisions using only complete clinical baseline data and imaging data, without any assistance from the AI model.
AI-Assisted Evaluation
Physicians evaluate the HCC cases and provide final staging and treatment decisions after reviewing the initial predictions and related evidence generated by the self-developed artificial intelligence (AI) model, alongside the clinical baseline and imaging data.
Locations (1)
Beijing Tsinghua Changgung Hospital
Beijing, Changping, China