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Optimizing Early Nutrition Management of Extremely and/or Very Preterm Infants
Sponsor: Children's Hospital of Fudan University
Summary
A clinical quality improvement bundle on early nutrition supplementation is developed to improving the clinical outcomes (including growth, organ function, and neurodevelopment outcomes) of extremely and/or very preterm infants. This bundle consists of three aspects: individualized and precise human milk feeding, early enteral zinc supplementation, and routine parenteral carnitine supplementation.
Official title: Optimizing Early Nutrition Management of Extremely and/or Very Preterm Infants Based on Best Clinical Practice: a Real Word Study
Key Details
Gender
All
Age Range
Any - 1 Day
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-04-01
Completion Date
2029-12-31
Last Updated
2026-04-20
Healthy Volunteers
No
Interventions
A nutritional improving bundle for the intervention group
The intervention group will receive an additional nutritional bundle based on the routine nutritional strategies for the control group. The bundle include individualized and precise breastfeeding, early enteral zinc supplementation, and routine parenteral carnitine supplementation.
Routine nutritional strategies for the control group
The control group consisted of retrospectively enrolled subjects matched with the intervention group. They received only the nutritional supplementation strategies routinely used in clinical practice at the time, including standard human milk fortification, zinc supplementation based on serological markers, and lower-dose carnitine supplementation.
Locations (1)
Children's Hospital of Fudan University
Shanghai, China