Clinical Research Directory

Inclusion Criteria: * Patient or legally authorized representative (LAR) provides authorization and/or consent per institution and geographical requirements * Patient is not cognitively impaired, pregnant, prisoner, employed by Northwell, uninsured, or a student * Age 18-75 years old with the ability to consent for the procedure * Patient is consented within the enrollment window of the therapy received, as applicable * Patients with frequent (\>10%) or symptomatic PVCs with ECG morphology consistent with papillary muscle origin. * Papillary muscle PVCs in setting of cardiomyopathy. * Patients prescribed by their treating physician to undergo the procedure with the Optrell™ mapping catheter as part of routine clinical care. * Patient demonstrates proficiency in the English language; reading, writing, and conversational Exclusion Criteria: * Patient who is, or is expected to be, inaccessible for follow-up * Participation is excluded by local law * Patient is currently enrolled or plans to enroll in concurrent drug/device study that may confound the study results * Unable to consent * PVC from site other than papillary muscle * Acute coronary syndrome * Congestive heart failure in acute decompensation * Rapid atrial fibrillation * Requiring ventricular pacing