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Comparison of Propofol and Propofol-Ketamine Anesthesia on Optic Nerve Sheath Diameter in Endovascular Cerebral Aneurysm Procedures
Sponsor: Ankara City Hospital Bilkent
Summary
This study aimed to compare the effects of propofol-based anesthesia and propofol-ketamine anesthesia on optic nerve sheath diameter (ONSD) in patients undergoing elective endovascular treatment of unruptured intracranial aneurysms. ONSD, measured using ultrasonography, is a non-invasive surrogate marker of intracranial pressure. In addition, intraoperative hemodynamic parameters, cerebral oxygenation, and anesthetic requirements were evaluated to assess the safety and physiological impact of the two anesthesia techniques.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
46
Start Date
2025-06-15
Completion Date
2026-01-01
Last Updated
2026-04-21
Healthy Volunteers
No
Interventions
Propofol (Astra-Zeneca)
General anesthesia maintained with propofol-based technique during endovascular treatment of unruptured intracranial aneurysms
Propofol and Ketamine Mixture (Ketofol)
General anesthesia maintained with a combination of propofol and ketamine during endovascular treatment of unruptured intracranial aneurysms.
Locations (1)
Ankara City Hospital Bilkent
Ankara, Turkey (Türkiye)