Clinical Research Directory
Browse clinical research sites, groups, and studies.
Clinical Outcomes After Non-curative Endoscopic Resection in Early Colorectal Cancer: A Multicenter Study
Sponsor: Nanfang Hospital, Southern Medical University
Summary
This multicenter study aims to evaluate clinical outcomes and optimize management strategies in patients with early colorectal cancer who undergo non-curative endoscopic resection. Patients with non-curative resection following endoscopic treatment will be enrolled across multiple centers and managed according to real-world clinical decisions, including additional surgery or surveillance. Baseline demographic, endoscopic, and pathological characteristics will be systematically collected. The primary objective is to compare recurrence and survival outcomes between different management strategies. Secondary objectives include identifying prognostic factors associated with recurrence and developing a risk stratification model to guide individualized treatment decisions. All participants will undergo standardized follow-up according to clinical guidelines. This study is expected to provide real-world evidence to refine risk assessment, reduce unnecessary surgery, and improve personalized management for patients with early colorectal cancer after non-curative endoscopic resection.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2025-09-03
Completion Date
2028-12-01
Last Updated
2026-04-21
Healthy Volunteers
Not specified
Interventions
Additional Surgery
Additional surgical resection performed after non-curative endoscopic resection based on pathological risk factors and clinical indications.
Surveillance
Active surveillance with regular endoscopic and imaging follow-up without additional surgical intervention.
Locations (3)
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
Shenzhen Longgang District People's Hospital
Shenzhen, Guangdong, China
The Second Affiliated Hospital of Guangzhou Medical University
Haizhu, Guangzhou, China