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Effectiveness of Serratiopeptidase After Mandibular Third Molar Surgery
Sponsor: Sharif Medical Research Center
Summary
This randomized controlled trial was conducted to compare the effect of serratiopeptidase versus no intervention on postoperative mouth opening, swelling, and trismus following surgical removal of mesioangular mandibular third molars.
Official title: Efficacy of Serratiopeptidase After Surgical Removal of Mesioangular Mandibular Third Molars: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
110
Start Date
2025-06-06
Completion Date
2025-09-02
Last Updated
2026-04-21
Healthy Volunteers
Yes
Conditions
Interventions
Serratiopeptidase
Serratiopeptidase was administered postoperatively following surgical removal of a mesioangular mandibular third molar as an adjunct to standard postoperative care to reduce postoperative pain, swelling, and inflammation.
Standard Postoperative Care
Routine postoperative management following surgical removal of a mesioangular mandibular third molar without serratiopeptidase, including prescribed analgesics, antibiotics if indicated, and postoperative instructions.
Locations (1)
Sharif medical and dental college, jati umra.
Lahore, Punjab Province, Pakistan