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Effect of a Non-pharmacological Intervention on Endothelial Function, Body Composition, and Physical Functionality in Recovered COVID-19 Patients.
Sponsor: Instituto Nacional de Enfermedades Respiratorias
Summary
This study aims to evaluate the impact of a non-pharmacological treatment (nutritional therapy and pulmonary rehabilitation) on endothelial function, body composition, and physical functionality in recovered COVID-19 patients. The primary research question is: What is the effect of a non-pharmacological treatment (nutritional therapy and pulmonary rehabilitation) on endothelial function, body composition, and physical capacity in recovered COVID-19 patients, compared to those receiving conventional medical management? A nutritional treatment combined with L-citrulline supplementation (intervention group) will be compared against conventional treatment alone (control group). Both groups will undergo pulmonary rehabilitation for a 3-month follow-up. Subjects assigned to the intervention group will be required to: * Take 4 g of L-citrulline daily for 3 months. * Attend an interim session at 1.5 months for review of the nutritional treatment and supplementation. * Keep a record of each supplement intake.
Official title: Effect of a Non-pharmacological Intervention (Nutritional Therapy and Pulmonary Rehabilitation) on Endothelial Function, Body Composition, and Physical Functionality in Recovered COVID-19 Patients.
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
43
Start Date
2020-11-09
Completion Date
2023-08-10
Last Updated
2026-04-22
Healthy Volunteers
No
Conditions
Interventions
L-citrulline supplementation
Subjects allocated to the intervention group receive 4 grams of L-citrulline supplementation daily, combined with nutritional therapy, over a 3-month period.
Locations (1)
Instituto Nacional de Enfermedades Respiratorias
Mexico City, Mexico