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NOT YET RECRUITING
NCT07544498
NA

XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers

Sponsor: Medical University of Graz

View on ClinicalTrials.gov

Summary

This study investigates the effectiveness of an extended reality (XR) based resilience training program designed to support the mental health and well-being of nurses working in hospital settings. Nurses are exposed to high emotional, cognitive, and organizational demands and show elevated levels of work-related stress and stress-associated mental health problems. Strengthening resilience and coping capacities is therefore an important preventive approach to support nurses' well-being and sustain quality of care. The study is conducted as a pragmatic randomized controlled trial with a waitlist control group and includes approximately 232 nurses from hospitals in several European countries. Participants are randomly assigned either to an XR-based resilience training group or to a waitlist control group that continues with care as usual during the waiting period. The XR-based intervention consists of eight immersive training sessions delivered over approximately ten weeks using a head-mounted display. The training focuses on behavioral, cognitive, and emotional coping strategies and aims to enhance key resilience factors such as problem-solving, cognitive reappraisal, emotion regulation, and positive self-care. The primary outcome is perceived stress, assessed using the Perceived Stress Scale. Secondary outcomes include resilience, occupational self-efficacy, quality of life, psychological distress, burnout symptoms, coping strategies, work-related rumination, and turnover intentions. Assessments are conducted at baseline, post-intervention, and at a 20-week follow-up. In addition, a subgroup of participants will optionally provide physiological data during selected XR sessions to explore digital biomarkers related to stress and recovery. The findings of this study will provide evidence on the effectiveness, feasibility, and acceptance of XR-based resilience training for nurses and inform future implementation of digital mental health interventions in healthcare workplaces.

Official title: A Pragmatic Randomized Controlled Trial Study Protocol: XR2ESILIENCE - Pioneering XR Technology for the Promotion of Resilience and Mental Health of the Healthcare Workforce

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

232

Start Date

2026-09

Completion Date

2028-03

Last Updated

2026-05-18

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

XR-based Resilience Training

The XR-based resilience training is delivered via a standalone extended reality head-mounted display and consists of eight immersive sessions over approximately ten weeks. The training addresses behavioral coping strategies such as problem solving, cognitive coping strategies such as appraisal and reappraisal of stressors, and emotional coping strategies including emotion regulation and positive self-care. Sessions last approximately 20 to 30 minutes and are completed individually with technical support available if needed.

OTHER

Waitlist Control

Participants assigned to the waitlist control condition receive no active intervention during the initial study period and continue with care as usual. After completion of the post-intervention assessment, participants are offered access to the XR-based resilience training.

Locations (8)

Medical University of Graz, Clinical Division of Psychiatry and Psychotherapeutic Medicine

Graz, Styria, Austria

Klinika za psihijatriju Sveti Ivan

Zagreb, Croatia

University Medical Center of Johannes Gutenberg University Mainz

Mainz, Rhineland-Palatinate, Germany

Hospital José Joaquim Fernandes

Beja, Beja District, Portugal

Del Henares University Hospital

Coslada, Madrid, Spain

Summa 112

Madrid, Madrid, Spain

Infanta Leonor University Hospital

Madrid, Madrid, Spain

Infanta Sofía University Hospital

San Sebastián de los Reyes, Madrid, Spain