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XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers
Sponsor: Medical University of Graz
Summary
This study investigates the effectiveness of an extended reality (XR) based resilience training program designed to support the mental health and well-being of nurses working in hospital settings. Nurses are exposed to high emotional, cognitive, and organizational demands and show elevated levels of work-related stress and stress-associated mental health problems. Strengthening resilience and coping capacities is therefore an important preventive approach to support nurses' well-being and sustain quality of care. The study is conducted as a pragmatic randomized controlled trial with a waitlist control group and includes approximately 232 nurses from hospitals in several European countries. Participants are randomly assigned either to an XR-based resilience training group or to a waitlist control group that continues with care as usual during the waiting period. The XR-based intervention consists of eight immersive training sessions delivered over approximately ten weeks using a head-mounted display. The training focuses on behavioral, cognitive, and emotional coping strategies and aims to enhance key resilience factors such as problem-solving, cognitive reappraisal, emotion regulation, and positive self-care. The primary outcome is perceived stress, assessed using the Perceived Stress Scale. Secondary outcomes include resilience, occupational self-efficacy, quality of life, psychological distress, burnout symptoms, coping strategies, work-related rumination, and turnover intentions. Assessments are conducted at baseline, post-intervention, and at a 20-week follow-up. In addition, a subgroup of participants will optionally provide physiological data during selected XR sessions to explore digital biomarkers related to stress and recovery. The findings of this study will provide evidence on the effectiveness, feasibility, and acceptance of XR-based resilience training for nurses and inform future implementation of digital mental health interventions in healthcare workplaces.
Official title: A Pragmatic Randomized Controlled Trial Study Protocol: XR2ESILIENCE - Pioneering XR Technology for the Promotion of Resilience and Mental Health of the Healthcare Workforce
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
232
Start Date
2026-09
Completion Date
2028-03
Last Updated
2026-05-18
Healthy Volunteers
Yes
Interventions
XR-based Resilience Training
The XR-based resilience training is delivered via a standalone extended reality head-mounted display and consists of eight immersive sessions over approximately ten weeks. The training addresses behavioral coping strategies such as problem solving, cognitive coping strategies such as appraisal and reappraisal of stressors, and emotional coping strategies including emotion regulation and positive self-care. Sessions last approximately 20 to 30 minutes and are completed individually with technical support available if needed.
Waitlist Control
Participants assigned to the waitlist control condition receive no active intervention during the initial study period and continue with care as usual. After completion of the post-intervention assessment, participants are offered access to the XR-based resilience training.
Locations (8)
Medical University of Graz, Clinical Division of Psychiatry and Psychotherapeutic Medicine
Graz, Styria, Austria
Klinika za psihijatriju Sveti Ivan
Zagreb, Croatia
University Medical Center of Johannes Gutenberg University Mainz
Mainz, Rhineland-Palatinate, Germany
Hospital José Joaquim Fernandes
Beja, Beja District, Portugal
Del Henares University Hospital
Coslada, Madrid, Spain
Summa 112
Madrid, Madrid, Spain
Infanta Leonor University Hospital
Madrid, Madrid, Spain
Infanta Sofía University Hospital
San Sebastián de los Reyes, Madrid, Spain