Clinical Research Directory
Browse clinical research sites, groups, and studies.
HeartLogic™ in Patients With Heart Failure.
Sponsor: Poitiers University Hospital
Summary
This randomized, multicenter clinical trial will evaluate whether remote management guided by the HeartLogic™ algorithm improves outcomes compared with traditional face-to-face follow-up in adult patients with heart failure recently implanted with a HeartLogic™-enabled ICD or CRT-D device. The primary objective is to determine whether this strategy reduces, at 12 months, the proportion of patients with death, unscheduled hospitalization for heart failure, or deterioration in quality of life. Secondary objectives include assessment of hospitalization, mortality, quality of life, safety, and cost-effectiveness.
Official title: HeartLogic™ Evaluation for Remote Monitoring vs. Office-based Follow-up in Patients With Heart Failure.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
578
Start Date
2026-04-29
Completion Date
2029-05-15
Last Updated
2026-06-24
Healthy Volunteers
No
Conditions
Interventions
Alert-guided remote follow-up
Participants assigned to this intervention will receive alert-guided remote follow-up for heart failure. Device-generated alerts suggestive of worsening heart failure will be reviewed by the study team through the remote monitoring platform. When an alert occurs, patients may be contacted for symptom assessment and clinical evaluation, and treatment may be adjusted preemptively according to a predefined care pathway and local clinical practice.
Traditional follow up
Patients will be monitored every 6 months as recommended by the guidelines
Locations (15)
University hospital of Amiens
Amiens, France
University hospital of Brest
Brest, France
University hospital of Caen
Caen, France
University hospital of Grenoble
Grenoble, France
University hospital of Lille
Lille, France
La Timone University hospital
Marseille, France
Hopital du Confluent
Nantes, France
University hospital of Nantes
Nantes, France
Georges Pompidou European hospital
Paris, France
La Pitié Salpétrière
Paris, France
University hospital of Poitiers
Poitiers, France
University hospital of Rouen
Rouen, France
Pasteur clinic
Toulouse, France
University hospital of Toulouse
Toulouse, France
University hospital of Tours
Tours, France