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RECRUITING
NCT07546292
NA

Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation

Sponsor: Silvia Brem

View on ClinicalTrials.gov

Summary

This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning. Adult participants with a range of reading abilities will receive transcranial random noise stimulation (tRNS) while they perform an artificial orthography learning task. This task simulates letter-speech sound learning, an important first step during reading acquisition known to be impaired in individuals with developmental dyslexia. The effects of the intervention will be assessed using both behavioral measures and functional magnetic resonance imaging (fMRI).

Official title: Transcranial Electrical Stimulation and the Reading Brain: Toward Novel Interventions for Reading Impairments

Key Details

Gender

All

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-04-23

Completion Date

2027-06

Last Updated

2026-05-22

Healthy Volunteers

Yes

Interventions

OTHER

Transcranial random noise stimulation

Participants will receive high-frequency tRNS (max. 1.5 mA) applied to the left superior temporal gyrus. A high-definition setup (3x1 electrodes) will be used to achieve more focal stimulation. Stimulation will be applied during an artificial orthography learning task with simultaneous fMRI acquisition.

OTHER

Sham Stimulation

Participants will also have electrodes placed on their scalp. The setup is programmed to induce a short ramp-up of the chosen electrical current followed by a ramp-down at the beginning and at the end of the stimulation. In between, no current will be applied. Sham stimulation will be applied during an artificial orthography learning task with simultaneous fMRI acquisition.

Locations (1)

University Hospital of Psychiatry

Zurich, Switzerland