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The Effectiveness of Topical Prilocaine-Lidocaine Cream Plus Acetaminophen and Naproxen Compared to Lidocaine Injection Plus Acetaminophen and Naproxen to Manage Pain During IntraUterine Device Insertion
Sponsor: Monakshi Sawhney
Summary
The goal of this clinical trial is to learn if two pain medications used to treat pain during intrauterine device insertions work in persons with a uterus. It will also learn about the safety of the two study medications. The main questions it aims to answer are: Does prilocaine lidocaine, acetaminophen and naproxen or lidocaine injection, acetaminophen and naproxen reduce pain during intrauterine device insertions. Researchers will compare prilocaine lidocaine cream and lidocaine injection to see if it treats pain during an intrauterine device insertion. Participants will be asked to: * take acetaminophen and naproxen prior to the procedure. * receive either prilocaine-lidocaine or lidocaine injection during the procedure * to fill out a survey on past medical history, anxiety, and pain.
Official title: The PLAN IUD Trial: The Effectiveness of Topical Prilocaine-Lidocaine Cream Plus Acetaminophen and Naproxen Compared to Lidocaine Injection Plus Acetaminophen and Naproxen to Manage Pain During IntraUterine Device Insertion: A Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2026-04-14
Completion Date
2027-04-14
Last Updated
2026-04-22
Healthy Volunteers
Yes
Interventions
Prilocaine, Lidocaine
Participants in this arm will receive prilocaine lidocaine cream to their cervix (4 grams) to their cervix 5 minutes prior to the procedure.
Lidocaine HCl 1%
Participants will receive 1% lidocaine injected into the cervix (10mls) 5 minutes prior to the procedure
Locations (1)
Woodlawn Medical Clinic
Dartmouth, Nova Scotia, Canada