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CiNPWT Using in Mastectomy Wound Care After DIEP Flaps for Breast Reconstruction
Sponsor: Chiayi Christian Hospital
Summary
Background: Closed-incision negative pressure wound therapy (ciNPWT) is effective in reducing postoperative complications, yet its use in free flap breast reconstruction mastectomy wound remains controversial due to concerns that external pressure may compromise the microvascular pedicle. Methods: A retrospective comparative study was conducted on 253 patients (283 flaps) undergoing immediate DIEP flap reconstruction between 2012 and 2025. Patients were stratified into a ciNPWT group and a conventional dressing group. Outcomes included flap survival, wound complications, healing time, and length of stay (LOS). Multivariable regression models adjusted for confounders, including BMI and neoadjuvant chemotherapy.
Official title: Division of Plastic and Reconstruction Surgery
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
253
Start Date
2012-09-06
Completion Date
2025-12-31
Last Updated
2026-04-23
Healthy Volunteers
No
Interventions
Closed-Incision Negative Pressure Wound Therapy (CiNPWT)
Application of a negative pressure wound therapy system over primarily closed surgical incisions to reduce surgical site complications, including infection, seroma formation, wound dehiscence, and delayed wound healing.
Locations (1)
Ditmanson Medical Foundation Chiayi Christian Hospital
Chiayi City, Taiwan