Clinical Research Directory

Inclusion Criteria: * Adults aged 45-65 years. * Fully edentulous or partially edentulous maxilla requiring full-arch rehabilitation. * Sufficient maxillary bone volume to support at least four implants according to the All-on-X protocol. * Systemically healthy patients with no contraindications to dental implant surgery (ASA I-II classification). * Demonstrated ability to maintain adequate oral hygiene * Willingness to participate in the study and comply with follow-up visits and required maintenance protocols. * Patients seeking a fixed, implant-supported prosthesis for the maxilla due to missing teeth and inability to use removable prostheses effectively. * Acceptable radiographic findings with no signs of pathology, infection, or significant anatomical limitations. Exclusion Criteria: * Uncontrolled systemic diseases (e.g., uncontrolled diabetes, osteoporosis, immunosuppressive disorders) * History of radiation therapy to the head and neck region * Active periodontal disease or untreated caries * Maxillary cysts, tumors, or pathologies * Poor oral hygiene or inability to maintain postoperative care * Insufficient bone volume for All-on-X without extensive grafting * Maxillary sinus pathology or oroantral fistula * Psychiatric illness or cognitive impairment affecting compliance * Bruxism or parafunctional habits * Pregnant or lactating women * History of implant failure or titanium allergy * Use of bisphosphonates or antiresorptive medications * Heavy smoking (\>10 cigarettes/day) * Inability or unwillingness to attend follow-up visits * Diagnosed or symptomatic temporomandibular joint disorders (pain, clicking, locking, limited opening)