Clinical Research Directory

Inclusion Criteria: 1. Women aged 18-40, with regular menstruation (cycle from 21 to 35 days) and reduced fertility (infertility, early miscarriage, recurrent pregnancy loss, recurrent implantation failure, etc.) ; 2. Tests of ovarian reserve within 6 months: 1. AMH \< 1.1 ng/ml or (any day in cycle, refer to laboratory standards); 2. AFC \< 7 follicles or (any day in cycle); 3. Received \<3 cycles of IVF in public sector; 3. Subject has no history of allergy to TCM; 4. Subjects agree to receive IVF treatment upon the completion of this research within 12 weeks if they are not pregnant spontaneously; and 5. As diagnosed by Chinese Medicine practitioner through four diagnostic methods, suitable to receive Yulinzhu. Exclusion Criteria: 1. Previous history of a unilateral or bilateral oophorectomy; 2. Recent administration of TCM for DOR within 3 months; 3. Diagnosis of pregnancy, premature ovarian failure, residual follicles, cysts or space-occupying lesions in the ovary, pelvic inflammatory disease or polycystic ovary syndrome; and 4. Cancer, untreated thyroid dysfunction, severe cardiovascular/cerebrovascular diseases, severe liver/kidney diseases or hematopoietic system diseases. 5. Subjects are allowed to withdraw from the trial for one of the following reasons: (1) The patient fails to complete treatment due to safety or medical reasons; (2) The patient fails to follow treatment guidelines; (3) The patient is unwilling to continue treatment for any reason.