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Cognitive Musical Screening and Therapeutic Innovation in Multiple Sclerosis
Sponsor: Hunter College of City University of New York
Summary
This pilot study evaluates the effectiveness of screening and improving cognitive function in patients with multiple sclerosis (MS) using a musical tool, the Ipsilon. The Ipsilon performance will be compared with established neuropsychological assessments, including the Minimal Assessment of Cognitive Function in MS (MACFIMS) and the Processing Speed Test (PST). Thirty-two participants will be enrolled in a crossover design: half will complete the Ipsilon musical test for 15 minutes daily for seven consecutive days, while the other half will begin with no intervention before switching sequences. Participants will undergo screening for depression, colorblindness, musical background, and upper extremity function. Primary outcomes include evaluating whether the Ipsilon more reliably predicts cognitive domains measured by MACFIMS than the PST and assessing its potential to improve cognitive function. Secondary outcomes will examine associations with work functioning and quality of life.
Official title: Neurocognitive Musical Screening and Therapeutic Innovation: A Crossover Randomized Controlled Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
32
Start Date
2026-10-01
Completion Date
2028-12-31
Last Updated
2026-04-27
Healthy Volunteers
No
Conditions
Interventions
Musical tool (Ipsilon)
The musical tool to assess cognitive function