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NOT YET RECRUITING
NCT07552428

Cognitive Musical Screening and Therapeutic Innovation in Multiple Sclerosis

Sponsor: Hunter College of City University of New York

View on ClinicalTrials.gov

Summary

This pilot study evaluates the effectiveness of screening and improving cognitive function in patients with multiple sclerosis (MS) using a musical tool, the Ipsilon. The Ipsilon performance will be compared with established neuropsychological assessments, including the Minimal Assessment of Cognitive Function in MS (MACFIMS) and the Processing Speed Test (PST). Thirty-two participants will be enrolled in a crossover design: half will complete the Ipsilon musical test for 15 minutes daily for seven consecutive days, while the other half will begin with no intervention before switching sequences. Participants will undergo screening for depression, colorblindness, musical background, and upper extremity function. Primary outcomes include evaluating whether the Ipsilon more reliably predicts cognitive domains measured by MACFIMS than the PST and assessing its potential to improve cognitive function. Secondary outcomes will examine associations with work functioning and quality of life.

Official title: Neurocognitive Musical Screening and Therapeutic Innovation: A Crossover Randomized Controlled Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

32

Start Date

2026-10-01

Completion Date

2028-12-31

Last Updated

2026-04-27

Healthy Volunteers

No

Interventions

BEHAVIORAL

Musical tool (Ipsilon)

The musical tool to assess cognitive function