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Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients
Sponsor: Hospices Civils de Lyon
Summary
Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients. CRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure. Although CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability. The perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport. Because PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.
Official title: Correlation Between Capillary Refilling tIme and Perfusion Index in Critically Ill Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
267
Start Date
2026-04-29
Completion Date
2026-09-28
Last Updated
2026-09-02
Healthy Volunteers
No
Interventions
Microcirculation monitoring
Microcirculation monitoring by Capillary Refill Time (CRT) measurements
Microcirculation monitoring
Microcirculation monitoring by Perfusion Index (PI) measurements
Locations (2)
Service de Réanimation cardio-vasculaire et thoracique, Hôpital Cardiologique louis Pradel, Hospices Civils de Lyon
Bron, France
Service de Médecine Intensive-Réanimation, Hôpital Édouard Herriot, Hospices Civils de Lyon
Lyon, France