Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT07555041

Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients

Sponsor: Hospices Civils de Lyon

View on ClinicalTrials.gov

Summary

Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients. CRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure. Although CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability. The perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport. Because PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.

Official title: Correlation Between Capillary Refilling tIme and Perfusion Index in Critically Ill Patients

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

267

Start Date

2026-04-29

Completion Date

2026-09-28

Last Updated

2026-09-02

Healthy Volunteers

No

Interventions

OTHER

Microcirculation monitoring

Microcirculation monitoring by Capillary Refill Time (CRT) measurements

OTHER

Microcirculation monitoring

Microcirculation monitoring by Perfusion Index (PI) measurements

Locations (2)

Service de Réanimation cardio-vasculaire et thoracique, Hôpital Cardiologique louis Pradel, Hospices Civils de Lyon

Bron, France

Service de Médecine Intensive-Réanimation, Hôpital Édouard Herriot, Hospices Civils de Lyon

Lyon, France