Clinical Research Directory

Inclusion Criteria: * Healthy subject and good general health * Man and woman * Between 18 and 65 years * Phototype II to IV (Fitzpatrick Classification scale) * BMI between 18.5 and 29.9 * With dark brown or black hair at the root * Subject agreeing to take the given Nutricosmetic: 2 capsules per day during 6 months and not introduce new nutritional supplement during the study. * Subject agreeing to not change sport activities (type and frequency of activities) throughout the entire course of the study * Subject agreeing to a stable diet with no change of dietary habits, e.g. no start a fasting cure throughout the entire course of the study * Subject agreeing to keep the same hair dyeing and frequency (if dyeing) during the whole study and at least from the previous month of starting. * Subject agreeing to keep the same shampoo frequency during all the whole study. * Subject with a stade IIIv or IV on the Hamilton scale amended by Norwood for men and with a grade I on the Ludwig scale for women. * Proportion of hair in telogen phase ≥ 20% for the men and ≥ 15% for the women. * Subject with a total hair density ≥ 150 hair/cm² on test area. * Subject agreeing to have one shaved zone of 1.2 x 1.5cm on the vertex area at each visit and during the whole study. * Subject accepting to have hair lock of about 135 hairs cut on D0 and M6 * Subject with a minimum hair length of 6 cm on the vertex and accepting to keep this minimum length during the study. * Having given freely and expressly his/her informed consent. * Psychologically able to understand the study related information and to give a written informed consent. * Affiliated to a health social security system. * Female of childbearing potential must use a medically accepted contraceptive regimen since at least 12 weeks before the beginning of the study and during all the study. * Female subjects of childbearing potential must have a negative pregnancy test at the inclusion. * Subject agreeing to no increase his/her cigarette and alcohol consumption during the study Exclusion Criteria: * Pregnant or nursing woman or planning a pregnancy during the study. * Subject with white or blond hair (coloured white hair also excluded to avoid affecting the PTG count); * Subject wearing a wig. * Subject with frizzy hair. * Subject having performed a hair bleaching or perm in the last 6 months or planned during the study. * Subject with modification of weight more than 5kg in the 2 months preceding the study and during the study, not using weight loss program or medication. * Subject having performed a visit to sauna or hammam in the 2 weeks preceding the study * Subject having wounds, moles, tattoos, scars, irritated skin… in the test areas that could influence the study. * Subject who had been deprived of their freedom by administrative or legal decision or who is under guardianship. * Major subject who is under guardianship or who is not able to express his/her consent. * Subject in a social or sanitary establishment. * Subject suspected to be non-compliant according to the investigator's judgment. * France only: Subject having received 6000 euros indemnities for participation in clinical research in the 12 previous months, including participation in the present study. * Subject enrolled in another clinical trial or which exclusion period is not over. * Intensive exposure to sunlight or UV-rays 1 month before the study or planned during the study. * Subject employed at the study site. * Subject with a condition or receiving a medication which, in the investigator's judgment, put the subject at undue risk. * Subject suffering from a severe or progressive disease (AIDS, HIV-positive, infection hepatitis, insulin dependent diabetes mellitus, epilepsy, chronic gastrointestinal disease…) or any other pathology that may interfere with the evaluation of the study results and/or subject safety at the investigator appreciation. * Subject having history of severe allergy or anaphylactic shock. * Subject having history of diabetes (type I or type II) * Subject having antecedent of cancer. * Subject with known hypersensitivity or allergy to one of the components of the products. * Subject with known history of or suffering from autoimmune disease and/or immune deficiency. * Subject having had surgery under general anaesthesia in the month preceding the start of the study. * Dermatological scalp disorders (ex: psoriasis, scalp dermatitis including seborrheic dermatitis, eczema, pre-cancerous or cancerous lesions, alopecia areata, fungal or bacterial infection, ringworm, lice or flea infestation) or poor hygiene. * Subject having skin disease on the head that requires actual topical medication or systemic drugs * Suffering from alopecia of special origins: chimiotherapy-induced (intoxication, drugs), or result from a chronic disease (genetic, endocrinological (excluding androgenetic alopecia)), immunological deficiencies…), result from injury or skin damage, alopecia of infectious origin (mycosis…), cicatricial alopecia, psychological disorders (trichotillomania, trichokryptomania). * Subject using minoxidil, finosteride, or other anti-hair loss treatment (including local hormonal treatment) within the past 6 months and during the study. * All other medical treatment (topic or per os) likely to interfere on hair growth or hair loss during the last 6 months prior the screening visit (including prostaglandins, rubefacients agents, all vasodilators, anti-androgens, all local hormonal treatment, silica, silicon, etc…); * Subject using anti-androgenic medications or drugs causing hypertrichosis (ex: phenytoin, acetazolamide, cyclosporine, diazoxide, psoralens, penicillamine, streptomycin, prostaglandins, vasodilatators and cortisone) or hypotrichosis (ex: anti-coagulants, retinoids, lithium and beta blockers) within the past 6 months and during the study. * Subject following a long period (\>30 days) treatment of anti-inflammatory during the last 4 months before the start of the study (screening) * Subject using any product having an action on hair loss, an anti-dandruff effect, fortifying effect or an effect on hair weakness within the 2 weeks before the study and during the study (shampoo, conditioner, leave on product applied by friction). Styling products (gel, hairspray, etc) are allowed during the study except on visit days with phototrichogram measurements. * Subject taking food supplements (including vitamins and minerals) or other active compounds which may have an effect on hair, scalp, skin, nail, … 2 months prior to the start of the study and throughout the entire course of the study * Subject having had hair implants, surgical intervention or aesthetic procedure for capillary correction or intending to have recourse to this surgery during the study. * Subject with application of a treatment (oral or topical) with tretinoin or isotretinoin or corticosteroid 8 weeks prior to the start of the study and/or throughout the entire course of the study * Subject with systemic therapy with immuno-suppressive drugs (e.g. corticosteroids) throughout the entire course of the study * Subject with systemic long-term therapy with anti-phlogistic agents or analgesics (e.g. diclophenac), except for minor pain relief medicine like acetylsalicylic acid or paracetamol within the last 3 days prior to the start of the study * Subjects using antibiotic medication within the 2 weeks before the study and during all the study duration