Clinical Research Directory

Inclusion Criteria: Participants must meet all of the following criteria: 1. Age 18 to 90 years. 2. Willing and able to comply with the study protocol and data collection procedures, able to understand the purpose of the study, and willing to provide written informed consent. 3. Considered by the heart team to have an indication for coronary revascularization but to be at high risk for coronary artery bypass grafting, or the patient declines coronary artery bypass grafting, and PCI is considered potentially beneficial after heart team evaluation. 4. Left ventricular ejection fraction ≤35%, or left ventricular ejection fraction ≤40% with severe mitral regurgitation. 5. Undergoing complex PCI with at least one of the following features: * Unprotected left main coronary artery disease; * PCI of the last remaining patent coronary artery; * Three-vessel coronary artery disease; * Calcified coronary lesion requiring rotational atherectomy; * Chronic total occlusion requiring bilateral angiography or retrograde techniques. Exclusion Criteria: Participants meeting any of the following criteria will be excluded: 1. Acute ST-segment elevation myocardial infarction within 1 week before enrollment. 2. Cardiogenic shock, defined by all of the following: * Systolic arterial blood pressure \<90 mmHg for ≥30 minutes, or need for vasopressors, inotropes, or mechanical circulatory support to maintain systolic arterial blood pressure ≥90 mmHg; * Evidence of reduced cardiac output, such as cardiac index \<2.2 L/min/m²; * Evidence of end-organ hypoperfusion, including cold extremities, urine output \<30 mL/hour, altered mental status, or lactate \>2 mmol/L. 3. Unable to complete the planned follow-up. 4. Any other condition that, in the opinion of the investigator, makes the patient unsuitable for participation in the registry.