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RECRUITING
NCT07557706
PHASE1

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Sponsor: University of Alabama at Birmingham

View on ClinicalTrials.gov

Summary

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2025-09-15

Completion Date

2026-12-31

Last Updated

2026-06-18

Healthy Volunteers

No

Interventions

DEVICE

transcutaneous auricular vagus nerve stimulation

Participants will sit quietly while receiving active nerve stimulation for 15 minutes. A gentle electrical current is delivered through hydrogel electrodes placed in the ear. The active stimulation parameters are set to 30 Hz, 250 µs, and 0.1-4 mA.

Locations (1)

Wellness, Health and Research Facility at UAB

Birmingham, Alabama, United States