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Donor Lifestyle and Nutritional Status, Blood Component Quality, and Patient Safety (ESENCIA)
Sponsor: Instituto Nacional de Perinatologia
Summary
The goal of this observational study is to evaluate how blood donors' lifestyle and nutritional status influence the quality of packed red blood cells (pRBCs) during storage and their impact on patient safety in transfused neonates and postpartum women. The main questions it aims to answer are: 1. Are donor lifestyle and nutritional profiles associated with the development of storage lesions in pRBCs? 2. Do these donor-related factors influence clinical outcomes after transfusion in neonates and postpartum women? 3. Are storage lesion in pRBCs associated with clinical outcomes in transfused neonates and postpartum women? Researchers will compare pRBC units stratified according to donor lifestyle and nutritional profiles to determine differences in storage lesion biomarkers and post-transfusion clinical outcomes.
Official title: Lifestyle of Blood Donors and Its Impact on the Quality of Blood Components During Storage and Patient Safety
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
OBSERVATIONAL
Enrollment
1014
Start Date
2026-07
Completion Date
2029-07
Last Updated
2026-04-30
Healthy Volunteers
Yes
Conditions
Locations (1)
Instituto Nacional de Perinatología
Mexico City, Mexico City, Mexico