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Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients
Sponsor: Antalya Training and Research Hospital
Summary
Delirium is a common complication in elderly intensive care unit (ICU) patients and is associated with poor clinical outcomes. Circadian rhythm disruption is considered an important contributing factor in delirium development. Stellate ganglion block (SGB) may modulate autonomic nervous system activity and improve circadian rhythm regulation. This prospective randomized placebo-controlled trial aims to evaluate the effects of ultrasound-guided stellate ganglion block on delirium incidence and circadian rhythm in ICU patients aged 65 years and older. Delirium will be assessed using validated clinical scales, and circadian rhythm will be evaluated through serial measurements of serum melatonin and plasma cortisol levels
Official title: Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients: A Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
65 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
130
Start Date
2026-04-01
Completion Date
2027-02-01
Last Updated
2026-04-30
Healthy Volunteers
No
Conditions
Interventions
stellate ganglion block with 0.5% bupivacaine
Ultrasound-guided stellate ganglion block will be performed in the supine position using 5 mL of 0.5% bupivacaine administered by an experienced anesthesiologist.
Placebo Injection
Ultrasound-guided sham procedure will be performed, consisting of 2 mL normal saline administered as an intramuscular injection into the anterolateral cervical region, without targeting the stellate ganglion.
Locations (2)
Antalya Training and Research Hospital
Antalya, Muratpaşa, Turkey (Türkiye)
Antalya Training and Research Hospital
Antalya, Muratpaşa, Turkey (Türkiye)