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ENROLLING BY INVITATION
NCT07558785
NA

Telemedicine Self-examination of Speech and Memory for Rapid Detection of Cognitive Impairments Using Machine Learning Methods

Sponsor: Faculty Hospital Kralovske Vinohrady

View on ClinicalTrials.gov

Summary

Early cognitive disorders diagnosis is becoming increasingly important due to population aging. The most common causes include Alzheimer's disease and frontotemporal dementia. These diseases are also manifested by changes in speech. NLP allows us to identify and classify these changes. The project aims to develop a web application for self-assessment and automated detection of cognitive disorders from speech. The application will have a form of a dialogue system using machine learning methods. The novelty of this approach is the possibility of an efficient self-assessment of a wide spectrum of the Czech population from their homes and an automated evaluation of test results. Early detection can be followed by a more detailed diagnosis and adequate treatment.

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

500

Start Date

2023-09-01

Completion Date

2026-08-31

Last Updated

2026-04-30

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)

A brief individually administered battery to measure cognitive decline or improvement across five domains in ages 12 to 89 years 11 months.

DIAGNOSTIC_TEST

the Mississippi Aphasia Screening Test

he Mississippi Aphasia Screening Test (MAST) was developed as a brief, repeatable screening measure for individuals with severely impaired communication/language skills.

DIAGNOSTIC_TEST

Amnesia Light and Brief Assessment (ALBA)

Very brief test used to measure deficits of more cognitive functions (short-term, episodic, semantic amnesia, sensory and motor aphasia, apraxia, psychomotor speed).

DIAGNOSTIC_TEST

The Picture naming and immediate recall test (PICNIR)

Very brief test used to measure deficits of more cognitive functions (short-term, episodic, semantic amnesia, sensory and motor aphasia, apraxia, psychomotor speed).

DIAGNOSTIC_TEST

Geriatric Depression Scale (GDS-15)

The Geriatric Depression Scale (GDS-15), used to screen for depression in adults aged 55 and older, consists of 15 items that assess mental health based on feelings over the past week.

DIAGNOSTIC_TEST

The Beck Anxiety Inventory (BAI)

A formative assessment and rating scale of anxiety.

DIAGNOSTIC_TEST

Digitial Diagnostics of Dementia (DDD)

Our experimental screening battery developed for this study.

Locations (3)

Západočeská univerzita v Plzni / Fakulta aplikovaných věd

Pilsen, Czechia

Faculty Hospital Kralovske Vinohrady

Prague, Czechia

Fyzikální ústav AV ČR, v. v. i.

Prague, Czechia