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Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)
Sponsor: Ankara City Hospital Bilkent
Summary
This retrospective observational study evaluates the clinical and radiological outcomes of patients with early-stage osteonecrosis of the femoral head treated with a combination of core decompression, stromal vascular fraction (SVF), and hyperbaric oxygen therapy (HBOT). A total of 24 patients were included and followed for two years. The aim of this study is to assess the effectiveness of this combined therapeutic approach in improving clinical outcomes and preventing disease progression.
Official title: Triple-Modal Therapy (Core Decompression, Stromal Vascular Fraction, and Hyperbaric Oxygen Therapy) is Associated Improved Clinical and Radiologic Outcomes in Early-Stage Osteonecrosis of the Femoral Head: Two-Year Follow-Up of 24 Patients
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
24
Start Date
2025-01-22
Completion Date
2025-11-22
Last Updated
2026-05-06
Healthy Volunteers
No
Conditions
Interventions
Core decompression
Surgical procedure performed to reduce intraosseous pressure and improve blood flow in the femoral head.
stromal vascular fraction (SVF)
Autologous stromal vascular fraction containing mesenchymal stem cells applied to enhance bone regeneration.
Hyperbaric Oxygen Therapy (HBOT)
Adjunctive hyperbaric oxygen therapy used to improve tissue oxygenation and promote healing.
Locations (1)
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)