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Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
Sponsor: Million Marker Wellness, Inc.
Summary
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial. The main questions this study aims to answer are: 1. If MM's 12-week EDC intervention program (EDC testing and report-back, EDC reduction curriculum) can reduce weight? 2. If a 12-week validated digital weight loss program can reduce EDC exposures? 3. What is the effectiveness of the two interventions at reducing weight and urinary EDC metabolites? Participants will be assigned to one of these two arms. Participants will collect their urine and blood samples pre- and post-intervention, and will take a comprehensive exposure survey before sending back their samples. This exposure survey will ask about participant's weight loss literacy, environmental health literacy, product use, diet, and lifestyle behaviors.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
226
Start Date
2025-08-18
Completion Date
2026-09
Last Updated
2026-08-18
Healthy Volunteers
No
Interventions
Educational curriculum
A self-directed online interactive curriculum of EDC material, with access to live coaches and an online forum.
Weight loss Application
A paid, self-directed weight loss application.
Urinary EDC metabolite testing
Mail-in urine samples tested for metabolites of bisphenols, phthalates, parabens, and oxybenzone.
Siphox clinic biomarker test
Mail-in blood samples tested for clinical biomarkers.
Weight loss reporting
Self-reported weight loss.
Locations (1)
Million Marker
Berkeley, California, United States