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Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation
Sponsor: Kalliopi Anna Poulia
Summary
This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice (Group C) on nutritional status, body composition and functional status in patients awaiting liver transplantation.
Official title: Evaluation of Protein Distribution Optimization With Exercise Regimen on Nutritional Status, Body Composition and Functional Status in Patients Awaiting Liver Transplantation: The POWER-LT Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-01-08
Completion Date
2029-07
Last Updated
2026-05-01
Healthy Volunteers
No
Interventions
Diet with even protein distribution plus exercise program
Diet of 1.2-1.5 g protein/kg dry body weight/day, equally divided (33.3% at 3 main meals) \| Exercise program: 3 days/week aerobic and 2 days/week resistance \| Duration: 12 weeks
Diet with skewed protein distribution plus exercise program
Diet of 1.2-1.5 g protein/kg dry body weight/day, unequally divided (10.0% at breakfast, 60.0% at lunch, 30.0% at dinner) \| Exercise program: 3 days/week aerobic and 2 days/week resistance \| Duration: 12 weeks
Standard dietary and physical activity advice
Standard dietary and physical activity advice \| Duration: 12 weeks
Locations (2)
Laiko General Hospital of Athens
Athens, Attica, Greece
Agricultural University of Athens
Athens, Attica, Greece