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COMPLETED
NCT07561281
NA

Low-Load BFR vs. High-Load Training on Biceps Hypertrophy

Sponsor: Mehmet Akif Ersoy University

View on ClinicalTrials.gov

Summary

This study aimed to compare the effects of low-load blood flow restriction resistance exercise (BFR-RE) performed to voluntary failure with traditional high-load resistance exercise (HL-RE) and a control condition on biceps brachii muscle hypertrophy, muscle stiffness, and maximal strength in untrained young men. Participants completed an 8-week training program, with exercise performed three times per week. Outcomes were assessed using ultrasound imaging, elastography, and one-repetition maximum (1RM) testing. The study evaluates whether low-load BFR training can produce adaptations comparable to high-load resistance training.

Official title: Bayesian Comparison of Low-Load Blood Flow Restriction and High-Load Resistance Exercise on Biceps Brachii Muscle Hypertrophy in Untrained Men

Key Details

Gender

MALE

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

33

Start Date

2025-06-01

Completion Date

2025-08-03

Last Updated

2026-05-07

Healthy Volunteers

Yes

Interventions

DEVICE

Blood Flow Restriction Resistance Exercise

Resistance exercise was performed under partial vascular occlusion using a pneumatic cuff applied to the upper arm. Limb occlusion pressure was individually determined, and exercise was conducted at a relative intensity corresponding to a percentage of one-repetition maximum. Occlusion pressure was maintained during sets and released between exercises. Training load and repetition tempo were standardized and progressively adjusted throughout the intervention period.

BEHAVIORAL

High-Load Resistance Exercise

Participants performed resistance exercise using conventional loading strategies based on a percentage of one-repetition maximum. Training intensity, volume, and progression were standardized across sessions, with loads adjusted periodically according to performance assessments.

Locations (1)

Karabük University Hasan Dogan Faculty of Sport Sciences

Karabük, Karabük Province, Turkey (Türkiye)