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COMPLETED
NCT07561281
NA

Low-Load BFR vs. High-Load Training on Biceps Hypertrophy

Sponsor: Mehmet Akif Ersoy University

View on ClinicalTrials.gov

Summary

This study aimed to compare the effects of low-load blood flow restriction resistance exercise (BFR-RE) performed to voluntary failure with traditional high-load resistance exercise (HL-RE) and a control condition on biceps brachii muscle hypertrophy, muscle stiffness, and maximal strength in untrained young men. Participants completed an 8-week training program, with exercise performed three times per week. Outcomes were assessed using ultrasound imaging, elastography, and one-repetition maximum (1RM) testing. The study evaluates whether low-load BFR training can produce adaptations comparable to high-load resistance training.

Official title: Bayesian Comparison of Low-Load Blood Flow Restriction and High-Load Resistance Exercise on Biceps Brachii Muscle Hypertrophy in Untrained Men

Key Details

Gender

MALE

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

33

Start Date

2025-06-01

Completion Date

2025-08-03

Last Updated

2026-05-01

Healthy Volunteers

Yes

Interventions

OTHER

Blood Flow Restriction Resistance Exercise

Resistance exercise was performed under partial vascular occlusion using a pneumatic cuff applied to the upper arm. Limb occlusion pressure was individually determined, and exercise was conducted at a relative intensity corresponding to a percentage of one-repetition maximum. Occlusion pressure was maintained during sets and released between exercises. Training load and repetition tempo were standardized and progressively adjusted throughout the intervention period.

OTHER

High-Load Resistance Exercise

Participants performed resistance exercise using conventional loading strategies based on a percentage of one-repetition maximum. Training intensity, volume, and progression were standardized across sessions, with loads adjusted periodically according to performance assessments.

Locations (1)

Karabük University Faculty of Sport Sciences

Karabük, Turkey (Türkiye)