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Comparison of Topical Insulin and Amniotic Membrane Transplant for Persistent Corneal Epithelial Defects
Sponsor: Al-Shifa Trust Eye Hospital
Summary
After an initial period of standard treatment, they received further care aimed at helping the surface of the eye heal. Clear instructions were given on how to use and store the treatment properly. Patients were then monitored regularly over several months, with doctors checking their healing progress during follow-up visits. The study continued for a total of 24 weeks to observe how well and how quickly the eye surface recovered.
Official title: Comparison of Efficacy of Topical Insulin With Amniotic Membrane Transplant in Persistent Epithelial Defects of Cornea
Key Details
Gender
All
Age Range
16 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
214
Start Date
2026-03-27
Completion Date
2026-09-27
Last Updated
2026-05-01
Healthy Volunteers
Yes
Conditions
Interventions
Topical insulin eye drops
Topical Insulin eye drops will be administered every 6 hours till healing of corneal epithelial defects
Amniotic Membrane Graft
Surgically amniotic membrane grafts will be applied to bridge and heal the corneal defects
Locations (1)
Al Shifa Eye Trust Hospital
Rawalpindi, Punjab Province, Pakistan