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PRP vs PRF in Management of Striae Distensae
Sponsor: Zagazig University
Summary
A split-side comparative clinical study evaluating the efficacy and safety of injectable platelet-rich fibrin (PRF) versus platelet-rich plasma (PRP), alone or combined with microneedling, in the treatment of striae distensae. Thirty patients received PRF or PRP on one side and combination therapy with microneedling on the contralateral side over five sessions. Outcomes included striae width, length, severity score, and patient satisfaction
Official title: Split-Side Comparative Clinical Study of Platelet-Rich Fibrin Versus Platelet-Rich Plasma With or Without Microneedling in Treatment of Striae Distensae
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-02-02
Completion Date
2026-02-17
Last Updated
2026-05-07
Healthy Volunteers
No
Conditions
Interventions
PRF group
Autologous platelet-rich fibrin prepared via single-spin centrifugation without anticoagulant and injected intradermally
PRP injection
Intradermal injection of platelet-rich plasma
PRF and microneedling
Performed using a dermapen device with 1 mm needle depth, followed by topical application of PRF.
PRP and microneedling
Performed using a dermapen device with 1 mm needle depth, followed by topical application of PRP.
Locations (1)
Zagazig University Hospitals
Zagazig, Zagazig--, Egypt