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Pentoxifylline for Prevention of Contrast Induced Nephropathy in Chronic Kidney Diseased Patients in Intensive Care Unit
Sponsor: Tanta University
Summary
The aim of this study is to evaluate the effect of pentoxifylline for control of contrast induced nephropathy in chronic kidney diseased patients in intensive care unit.
Official title: The Role of Pentoxifylline for Prevention of Contrast Induced Nephropathy in Chronic Kidney Diseased Patients in Intensive Care Unit
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2024-07-01
Completion Date
2025-06-01
Last Updated
2026-05-01
Healthy Volunteers
No
Interventions
Pentoxifylline
Patients received hydration (100ml normal saline every hour (2400ml/day) with closed dynamic monitoring of the blood volume and 400 mg oral Pentoxifylline (PTX) three times per day \[dose adjustment according to estimated glomerular filtration rate (eGFR)\] from 24 hr before contrast to 48 hr after contrast procedure.
Normal saline
Patient received hydration (100ml normal saline every hour (2400ml/day) with closed dynamic monitoring of the blood volume and placebo with same shape and color of Pentoxifylline (PTX) three times per day from 24 hr before contrast to 48 hr after contrast procedure.
Locations (1)
Tanta University
Tanta, El-Gharbia, Egypt