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NOT YET RECRUITING
NCT07562425
NA

Effects of Isometric, Isotonic, and Eccentric VMO Exercises in Patellofemoral Pain Syndrome

Sponsor: Firat University

View on ClinicalTrials.gov

Summary

Patellofemoral pain syndrome (PFPS) is a common musculoskeletal condition characterized by anterior knee pain, especially during activities such as stair climbing, squatting, running, and prolonged sitting. Weakness or delayed activation of the vastus medialis oblique (VMO) muscle is considered an important contributing factor in the development of PFPS. This study aims to compare the effects of three different types of VMO strengthening exercises (isometric, isotonic, and eccentric) applied within the terminal knee extension range (0-30°) on pain, functional performance, and muscle architecture in individuals with PFPS. Participants will be randomly assigned to one of three exercise groups. All participants will receive a standardized physiotherapy program, including heat therapy, TENS, and therapeutic ultrasound, followed by group-specific VMO strengthening exercises. The intervention will be performed three times per week for 8 weeks. Outcomes will be assessed before and after the intervention and will include pain intensity (Visual Analog Scale), functional performance (WOMAC, 30-second sit-to-stand test, and stair test), and muscle architecture parameters measured by ultrasound imaging. The results of this study are expected to provide evidence for optimizing rehabilitation strategies in individuals with PFPS.

Official title: Comparison of the Effects of Isometric, Isotonic, and Eccentric Vastus Medialis Oblique Strengthening Exercises Applied in Terminal Knee Extension Range on Pain, Function, and Muscle Architecture in Individuals With Patellofemoral Pain Syndrome: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2026-05-20

Completion Date

2026-08

Last Updated

2026-05-12

Healthy Volunteers

No

Interventions

OTHER

Isometric VMO Exercise

Isometric contractions of the vastus medialis oblique muscle will be performed with the knee supported at approximately 15° flexion, emphasizing maximal voluntary contraction without joint movement.

OTHER

Isotonic VMO Exercise

Participants will perform controlled concentric and eccentric contractions using ankle weights through a limited range of motion (0-30° knee extension).

OTHER

Eccentric VMO Exercise

Participants will perform eccentric contractions against resistance during knee flexion, with assisted concentric return to the starting position.

Locations (1)

Firat University

Elâzığ, MErkez, Turkey (Türkiye)