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COMPLETED
NCT07563491
NA

Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease

Sponsor: Muhammad Aamir Latif

View on ClinicalTrials.gov

Summary

Local literature is deprived of data comparing the effectiveness of esomeprazole and vonoprazan in patients with gastroesophageal reflux disease (GERD). This study was planned with the objective of comparing the effectiveness of esomeprazole versus vonoprazan in patients diagnosed with GERD.

Official title: Comparison of Effectiveness in Patients of Gastroesophageal Reflux Disease Taking Esomeprazole Versus Vonoprazan.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

824

Start Date

2025-01-01

Completion Date

2025-09-30

Last Updated

2026-05-04

Healthy Volunteers

No

Interventions

DRUG

Esomeprazole

Patients received a once-daily dose of 20 mg of esomeprazole after the evening meal for 4 weeks.

DRUG

Vonoprazan

Patients received a once-daily dose of 20 mg of vonoprazan after the evening meal for 4 weeks.

Locations (1)

Allama Iqbal teaching hospital

Dera Ghazi Khan, Punjab Province, Pakistan