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Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis
Sponsor: Faculty of Dental Medicine for Girls
Summary
This randomized placebo-controlled trial evaluated the effectiveness of zinc oxide ointment in the treatment of recurrent aphthous stomatitis (RAS). The study included 100 patients randomly assigned to receive either zinc oxide ointment or a placebo, applied three times daily for six days. Pain intensity was measured using a visual analogue scale (VAS), and oral health-related quality of life was assessed using OHIP-14 at baseline and on days 1, 3, and 6.
Official title: Evaluation of Zinc Oxide Ointment in Treatment of Recurrent Aphthous Stomatitis
Key Details
Gender
All
Age Range
16 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-06-30
Completion Date
2026-03-30
Last Updated
2026-05-04
Healthy Volunteers
No
Conditions
Interventions
zinc oxide
zinc oxide ointment that was formulated as in a polyethylene glycol base. The prepared ointment was evaluated for organoleptic properties such as odor, color, pH, smoothness, and spread ability
Placabo
A topical placebo ointment that was prepared the same as the test ointment without zinc oxide.
Locations (1)
Faculty of Dental Medicine for Girls ,Al-Azhar university
Cairo, Cairo Governorate, Egypt