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The Application of Biomarkers in the Care of Patients With Atrial Fibrillation
Sponsor: National Taiwan University Hospital
Summary
From 2020 to 2023, we established a longitudinal AF patient cohort with comprehensive clinical data collection. In our previous work, we utilized the Milliplex platform to screen 52 circulating biomarkers and identified several candidates potentially associated with AF burden. Building on these findings, the present study aims to further validate these biomarkers in a larger subset of patients (n=266) who completed paired pre- and post-intervention sampling. Targeted biomarkers may include NT-proBNP, IL-6, hs-CRP, Adipsin, GDF-15, sST-2, FABP3, and IGF-BP3. Our goal is to identify markers associated with AF burden, assess their predictive performance and subgroup consistency, and further elucidate the underlying pathophysiological mechanisms.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
266
Start Date
2026-01-01
Completion Date
2028-12-31
Last Updated
2026-05-04
Healthy Volunteers
No
Conditions
Locations (1)
National Taiwan University Hospita
Taipei, Taiwan