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COMPLETED
NCT07565376
NA

Effects of Exercise-Induced Muscle Damage on Neuromuscular Complexity

Sponsor: National and Kapodistrian University of Athens

View on ClinicalTrials.gov

Summary

This study will examine the effects of exercise-induced muscle damage, induced by eccentric exercise, on torque production, muscle oxygenation, and electromyographic activity of the knee extensors in healthy young men. Eleven participants will perform a sustained submaximal isometric contraction before and 48 hours after a muscle-damaging eccentric exercise protocol. It is anticipated that the eccentric exercise will confirm the presence of muscle damage, by decrease in maximal voluntary isometric torque, increase in muscle soreness, and reduction in pain-free range of motion. The effect of eccentric exercise on the complexity of torque output, which could be reflected by decreased Sample Entropy and increased DFA α, will be indicated by a possible shift toward more predictable and less adaptable motor control patterns. Based on these results, the investigators will know about the effect of eccentric exercise induced muscle damage on neuromuscular efficiency, that is greater neural input could be required to maintain the same mechanical output, as well as increased oxygen consumption in the active muscle.

Official title: Effects of Exercise-Induced Muscle Damage Induced by Eccentric Exercise on Knee Extensor Torque, Oxygenation, and Electromyographic Properties: A Complexity-Based Approach

Key Details

Gender

MALE

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

11

Start Date

2025-08-20

Completion Date

2026-03-30

Last Updated

2026-05-04

Healthy Volunteers

Yes

Interventions

OTHER

Isokinetic eccentric exercise

Isokinetic eccentric exercise consisted of 5 sets of 15 repetitions using the knee extensors. The intensity of the exercise was the maximal voluntary and an interval of 1 minute was applied between sets.

Locations (1)

School of Physical Education and Sport Science

Athens, Attica, Greece