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Effects of Exercise-Induced Muscle Damage on Neuromuscular Complexity
Sponsor: National and Kapodistrian University of Athens
Summary
This study will examine the effects of exercise-induced muscle damage, induced by eccentric exercise, on torque production, muscle oxygenation, and electromyographic activity of the knee extensors in healthy young men. Eleven participants will perform a sustained submaximal isometric contraction before and 48 hours after a muscle-damaging eccentric exercise protocol. It is anticipated that the eccentric exercise will confirm the presence of muscle damage, by decrease in maximal voluntary isometric torque, increase in muscle soreness, and reduction in pain-free range of motion. The effect of eccentric exercise on the complexity of torque output, which could be reflected by decreased Sample Entropy and increased DFA α, will be indicated by a possible shift toward more predictable and less adaptable motor control patterns. Based on these results, the investigators will know about the effect of eccentric exercise induced muscle damage on neuromuscular efficiency, that is greater neural input could be required to maintain the same mechanical output, as well as increased oxygen consumption in the active muscle.
Official title: Effects of Exercise-Induced Muscle Damage Induced by Eccentric Exercise on Knee Extensor Torque, Oxygenation, and Electromyographic Properties: A Complexity-Based Approach
Key Details
Gender
MALE
Age Range
18 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
11
Start Date
2025-08-20
Completion Date
2026-03-30
Last Updated
2026-05-04
Healthy Volunteers
Yes
Conditions
Interventions
Isokinetic eccentric exercise
Isokinetic eccentric exercise consisted of 5 sets of 15 repetitions using the knee extensors. The intensity of the exercise was the maximal voluntary and an interval of 1 minute was applied between sets.
Locations (1)
School of Physical Education and Sport Science
Athens, Attica, Greece