Clinical Research Directory
Browse clinical research sites, groups, and studies.
Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials
Sponsor: Medical University of Silesia
Summary
Tooth extraction is among the most common dental treatments. The procedure results in the formation of a bone defect. During the healing phase, the vertical and horizontal diameters of the alveolar ridge decrease, which has a negative impact on planned prosthetic or implantoprosthetic therapies. The socket preservation technique involves filling the socket with an augmentation biomaterial to reduce vertical and horizontal alveolar atrophy. This prospective clinical study compares two biomaterials suitable for alveolar ridge preservation: xenogeneic versus allogeneic. Histological analysis and radiographic parameters related to the dimensions of the alveolar ridge and bone optical density are evaluated during a 180-day follow-up period.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-08-05
Completion Date
2026-03-27
Last Updated
2026-05-04
Healthy Volunteers
No
Interventions
Socket preservation with xenograft
Minimally invasive tooth extraction with separation is performed. The wound is debrided and the socket is filled with xenogeneic biomaterial (Geistlich Bio-Oss®, cortico-cancellous bone powder, 0.25-1 mm granules) up to the alveolar crest. This is then covered with a Geistlich Bio-Gide® collagen membrane and sutured with 4-0 nylon sutures. An open healing protocol is utilised. Standardised postoperative care, antibiotics and follow-up are provided. CBCT scans with a 5x5 cm field of view are performed preoperatively, and again after 7-10 days and after 180 days of treatment.
Socket preservation with allograft
Minimally invasive tooth extraction with separation is performed. The wound is debrided and the socket is filled with allogeneic biomaterial (BIOBank®, cortico-cancellous bone powder, 0.5 mm granules) up to the alveolar crest. This is then covered with a Geistlich Bio-Gide® collagen membrane and sutured with 4-0 nylon sutures. An open healing protocol is utilised. Standardised postoperative care, antibiotics and follow-up are provided. CBCT scans with a 5x5 cm field of view are performed preoperatively, and again after 7-10 days and after 180 days of treatment.
Locations (2)
Department of Oral Surgery of the Medical University of Silesia in Bytom
Bytom, Silesian Voivodeship, Poland
"Comfortmed" dental clinic
Żory, Silesian Voivodeship, Poland