Clinical Research Directory

Inclusion Criteria: 1. Written informed consent must be obtained prior to any screening procedures 2. Clinically stable during two months prior to the study. This will be based upon clinical judgement. 3. On stable blood pressure medication 4 weeks prior to the study 4. Dialysis with a K3 dialysate 5. Adequate double-needle dialysis access (fistula or catheter) 6. Able to fill questionnaire/symptom score Exclusion Criteria: 1. Predialysis calcium \<1,9mmol/L during baseline 2. Magnesium predialysis \>1,45mmol/L during baseline 3. Patient has a history of child C liver cirrhosis 4. Coronary intervention \<3 months before randomization 5. Hospitalization \<2 months before randomization 6. Uncontrolled predialysis hypertension \>160/90mmHg despite 4 antihypertensive drugs 7. Predialysis blood pressure \<90mmHg during baseline visit 8. History of dialysis access related problems \<1 month before the randomization 9. Chronic Atrial fibrillation 10. NYHA class 4 heart failure 11. Any disorder, which in the investigator's opinion might jeopardise participant's safety or compliance with the CIP.