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Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis
Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital
Summary
Atherosclerotic renal artery stenosis is the most common cause of secondary hypertension , increasing the risk of cardiovascular and kidney-related complications. Some small-scale studies have suggested that covered stents are effective and safe, but high-quality evidence from large-scale studies in atherosclerotic renal artery stenosis remains limited. This study aims to evaluate whether covered stents are more effective than bare metal stents in patients with atherosclerotic renal artery stenosis. Eligible participants will be randomly assigned to receive either a covered stent or a bare metal stent. Patients will be followed for 12 months to assess Changes in eGFR, 24-hour systolic blood pressure, and 24-hour diastolic blood pressure from baseline to 12 months were compared among the groups. The results of this study may help improve treatment strategies and guide the selection of stent type for patients with this condition.
Official title: Endovascular Treatment of Atherosclerotic Renal Artery Stenosis: A Prospective Randomized Controlled Study Comparing Covered Stents and Bare Metal Stents
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2026-04-30
Completion Date
2028-04-30
Last Updated
2026-05-04
Healthy Volunteers
No
Interventions
Covered Stent
Endovascular implantation of a covered stent in the renal artery
Bare Metal Stent
Endovascular implantation of a bare metal stent in the renal artery.
Locations (15)
The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Fuwai Central China Cardiovascular Hospital
Zhengzhou, Henan, China
Zhengzhou Central Hospital Affiliated to Zhengzhou University
Zhengzhou, Henan, China
Nanjing Pukou People's Hospital(Liangjiang Hospital Southeast University)
Nanjing, Jiangsu, China
Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College)
Nanchang, Jiangxi, China
Affilated Zhongshan Hospital of Dalian University
Dalian, Liaoning, China
Frist Aiffiliated Hospital of Dalian Medical University
Dalian, Liaoning, China
Qilu Hospital of Shandong University
Jinan, Shandong, China
Qingdao Hospital University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital)
Qingdao, Shandong, China
The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu
Chengdu, Sichuan, China
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037
Beijing, China
Department of Cardiovascular Medicine, Cardiovascular Research Center , The First Affiliated Hospital of Chongqing Medical University
Chongqing, China
The Second Affiliated Hospital of Harbin Medical University, Ha'erbin
Harbin, China
China-Japan Union Hospital of Jilin University, Changchun, Lilin
Jilin, China