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NOT YET RECRUITING
NCT07567417
NA

Endocrinal Dysfunction Among Children With Dilated Cardiomyopathy

Sponsor: Sohag University

View on ClinicalTrials.gov

Summary

All patients in this study will be subjected to the following (as detailed in the attached patient's data sheet). 1. Clinical History: focusing on: * Socio-demographic factors, especially age, gender, family history, and degree of consanguinity. * Cardiac symptoms, such as feeding difficulties in the infant, exercise intolerance in older children, fatigue, dyspnea on exertion, heart failure symptoms. 2. Thorough clinical examination: focusing on: * General condition. * Anthropometric measures (weight, height, and body mass index). * Vital signs (Including HR, BP, SO2, RR, Body temperature). * Cardiac examination (including any associated murmur, signs up heart failure). 3. Severity of heart failure in children with dilated cardiomyopathy For all patients, they were classified according to Children's Ross HF classification. Children's Ross HF classification is as follows\[17\]: Class I: asymptomatic cases. Class II: mild tachypnea or diaphoresis with feeding in infants, dyspnea on exertion in older children. Class III: marked tachypnea or diaphoresis with feeding in infants, marked dyspnea on exertion, and prolonged feeding times with growth failure. Class IV: tachypnea, retractions, grunting, or diaphoresis at rest are examples of symptoms. 4. Data collection: according to attached checklist for every patient involved in the study

Official title: Endocrinal Dysfunction Among Children With Dilated Cardiomyopathy at Sohag University Hospital

Key Details

Gender

All

Age Range

1 Year - 12 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-06-01

Completion Date

2027-03-01

Last Updated

2026-05-05

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Echocardiography assessment.

Assessment of Ejection fraction, Fractional shortening, and LV diameters/volumes to confirm diagnosis and severity.

DIAGNOSTIC_TEST

Laboratory investigations and Hormone assessment.

Blood samples will be collected at 9:00 a.m. to measure IGF-1, free T3 and T4, TSH, morning serum cortisol, ACTH, 25 OH vit D, calcium, parathyroid hormones, prolactin, and electrolytes (Na, K).

Locations (1)

Pediatric department at Sohag University hospital

Sohag, Egypt