Clinical Research Directory
Browse clinical research sites, groups, and studies.
Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery
Sponsor: Columbia University
Summary
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery. When added to standard spinal anesthesia consisting of bupivacaine (a local anesthetic) and fentanyl and morphine (two opioids), these medications may decrease some of the pulling/tugging/pressure sensations that patients sometimes feel during cesarean delivery, may prolong the anesthetic time, and may decrease postoperative pain.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2026-06
Completion Date
2028-05
Last Updated
2026-05-05
Healthy Volunteers
No
Conditions
Interventions
Clonidine
30 mcg Clonidine will be given by intrathecal administration
Dexmedetomidine
4 mcg Dexmedetomidine will be given by intrathecal administration
Locations (1)
Columbia University Irving Medical Center/NewYork Presbyterian Hospital
New York, New York, United States