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A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
Sponsor: AbbVie
Summary
The objective of this study is to assess the effect of repeated doses of ABBV-722 on the single dose pharmacokinetics (PK) of Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin
Official title: A Phase 1 Study to Evaluate the Effect of Multiple Doses of ABBV-722 on the Pharmacokinetics of Cocktail Probe Substrates of CYP3A and Select Transporters in Healthy Adult Subjects
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2026-04-30
Completion Date
2026-07
Last Updated
2026-07-20
Healthy Volunteers
Yes
Conditions
Interventions
ABBV-722
Oral Tablet
Midazolam
Oral Solution
Metformin
Oral Tablet
Digoxin
Oral Tablet
Pitavastatin
Oral Tablet
Sitagliptin
Oral Tablet
Locations (1)
Acpru /Id# 282184
Grayslake, Illinois, United States