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Correlation of Cardiac Index Measured by the PRAM Method With NIRS and Lactate Levels in Pediatric Aortic Coarctation Surgery
Sponsor: Konya City Hospital
Summary
This prospective observational study aims to evaluate the correlation between cardiac index measured by the MostCare™ system (Pressure Recording Analytical Method, PRAM) and cerebral/renal regional oxygen saturation measured by near-infrared spectroscopy (NIRS) and arterial lactate levels in neonates and infants (body weight 2.5-3.5 kg, age 0-3 months) undergoing surgical repair of aortic coarctation. Measurements will be recorded at four intraoperative time points: after anesthesia induction, before aortic cross-clamp, 3 minutes after cross-clamp release, and at end of surgery. No additional intervention beyond standard anesthesia and surgical care will be applied.
Official title: Correlation of Cardiac Index Measured by the Pressure Recording Analytical Method (PRAM) With Near-Infrared Spectroscopy (NIRS) and Arterial Lactate Levels in Neonates and Infants Undergoing Surgical Repair of Aortic Coarctation: A Prospective Observational Study
Key Details
Gender
All
Age Range
Any - 3 Months
Study Type
OBSERVATIONAL
Enrollment
43
Start Date
2026-05
Completion Date
2027-03
Last Updated
2026-05-05
Healthy Volunteers
No
Conditions
Interventions
MostCare (PRAM)
Real-time, calibration-free cardiac index monitoring via arterial pressure waveform analysis using the MostCare™ system. Used as part of routine intraoperative hemodynamic monitoring.
Near-Infrared Spectroscopy (NIRS)
Non-invasive monitoring of regional cerebral and renal oxygen saturation (rSO2) using the INVOS™ oximeter as part of standard intraoperative care.
Arterial Blood Gas with Lactate
Arterial blood gas sampling for lactate measurement at four intraoperative time points as part of routine clinical monitoring.
Locations (1)
SBÜ Konya Şehir Hastanesi
Konya, Turkey (Türkiye)